American Heart Association

Visual Abstract: Proenkephalin and Renal Status in Heart Failure

Contributors: Ike Chinyere and Michela Brambatti

Proenkephalin, an Opioid System Surrogate, as a Novel Comprehensive Renal Marker in Heart Failure

Study Link: Proenkephalin, an Opioid System Surrogate, as a Novel Comprehensive Renal Marker in Heart Failure

NT-proBNP Levels Less Predictive in HFpEF with Atrial Fibrillation

Contributors: Ike Chinyere and Michela Brambatti

N-Terminal Pro-B-Type Natriuretic Peptide Levels for Risk Prediction in Patients With Heart Failure and Preserved Ejection Fraction According to Atrial Fibrillation Status

Study Link: N-Terminal Pro-B-Type Natriuretic Peptide Levels for Risk Prediction in Patients With Heart Failure and Preserved Ejection Fraction According to Atrial Fibrillation Status

Bonus! Waveform

NT-proBNP is more predictive of unfavorable outcomes in HFpEF in the absence of AFib

Contributor: Martin Chacon

Does an increased NT-proBNP in patients with atrial fibrillation (AF) and HFpEF correspond to a higher risk for worse outcomes? Kristensen et al suggest increased NTproBNP levels do not show the same correlation with poor outcomes in patients with AF compared with those without AF. NT-proBNP is increased in AF patients independently from heart failure, therefore, its capacity to predict cardiovascular death or hospitalizations in HFpEF may be diminished.

Hemodynamic Ramp Testing For More Accurate HVAD Tuning

Contributors: Ike Chinyere and Michela Brambatti

Impact of Hemodynamic Ramp Test-Guided HVAD Speed and Medication Adjustments on Clinical Outcomes The RAMP-IT-UP Multicenter Study

Study Link: Impact of Hemodynamic Ramp Test-Guided HVAD Speed and Medication Adjustments on Clinical Outcomes: The RAMP-IT-UP Multicenter Study

Visual Abstract: Cardiac Troponin I and Cardiac Events in HFpEF Patients

Contributor: Ike Chinyere

Cardiac Troponin I and Risk of Cardiac Events in Patients With Heart Failure and Preserved Ejection Fraction

Study Link: Cardiac Troponin I and Risk of Cardiac Events in Patients With Heart Failure and Preserved Ejection Fraction