Visual Abstract: Proenkephalin and Renal Status in Heart Failure
Contributors: Ike Chinyere and Michela Brambatti
Study Link: Proenkephalin, an Opioid System Surrogate, as a Novel Comprehensive Renal Marker in Heart Failure
NT-proBNP is more predictive of unfavorable outcomes in HFpEF in the absence of AFib
Contributor: Martin Chacon
Does an increased NT-proBNP in patients with atrial fibrillation (AF) and HFpEF correspond to a higher risk for worse outcomes? Kristensen et al suggest increased NTproBNP levels do not show the same correlation with poor outcomes in patients with AF compared with those without AF. NT-proBNP is increased in AF patients independently from heart failure, therefore, its capacity to predict cardiovascular death or hospitalizations in HFpEF may be diminished.
