Contributor: Elise Vo

Decoupling of diastolic pulmonary artery pressure and PCWP (greater than 5 mmHg difference) during ramp testing in continuous flow LVAD patients is a significant predictor for HF hospitalization and all-cause mortality. This decoupling is also represented as the diastolic pressure gradient (dPAP-PCWP). dPAP and PCWP decoupling (increased DPG) may indicate intrinsic pulmonary vascular pathology and associated right ventricular strain.