Kristina Shkirkova, BSc
The risk factors of stroke, a major contributor to the global burden of disability and mortality, include environmental exposure to air pollution. Pre-stroke long-term exposure to air pollution derived particulate matter is associated with higher mortality rates after ischemic stroke, the authors of the new study from China report.
The study by Chen et al. estimated the daily exposure of a cohort of 12291 ischemic stroke patients to air pollutants via a machine learning algorithm that accounted for temporal and spatial meteorological and satellite monitoring data for the geocoded location of patients’ home address. The authors looked at 3-year pre-stroke air levels of particulate matter with aerodynamic diameter ≤10 μm and nitrogen dioxide and the rates of mortality after ischemic stroke within 1 year follow up period between 2007 and 2008. Smaller coarse particles in the air mixture were the primary interest in this study, as they contain the most toxin and are able penetrate deeper through the respiratory system and cause an inflammatory response.