Symptomatic Intracranial Thrombus Characteristics, Collateral Blood Flow and Recanalization Rates With/Without Intravenous Alteplase in Mild Ischemic Stroke Patients
Andrew Micieli, MMI MD
Lau HL, Gardener H, Coutts SB, Saini V, Field TS, Dowlatshahi D, Smith EE, Hill DM, Romano JG, Demchuk AM, et al. Radiographic Characteristics of Mild Ischemic Stroke Patients With Visible Intracranial Occlusion: The INTERRSeCT Study. Stroke. 2021.
Vascular imaging of the head and neck in the hyperacute stroke setting has important diagnostic and prognostic implications, especially in patients with mild stroke. The presence of an intracranial large vessel occlusion is a strong predictor of early neurological and radiographic deterioration in patients with mild stroke. Recanalization is associated with improved functional outcomes; however, the safety in mild stroke patients is less clear.
The authors sought to analyze thrombus characteristics, collateral blood flow and recanalization rates with or without intravenous alteplase in patients with mild ischemic stroke (NIHSS ≤5) and compare these with patients with moderate/severe symptoms (NIHSS >5) from the previously published INTERRSeCT study.