Richard Jackson, MD
Nai-Fang Chi et al. published a study on the evaluation of autoregulation in ischemic stroke. The purpose of this study was to investigate whether dynamic cerebral autoregulation (dCA) indices constitute an independent functional outcome predictor of acute ischemic stroke.
Cerebral autoregulation (CA) regulates vascular tone to compensate hypoperfusion after during ischemia but no concrete guidelines for blood pressure targets are currently known. The impact of cerebral autoregulation is associated with infarct volume but outcome is currently confounded by other comorbid variables. Dynamic cerebral autoregulation (dCA) is a way to quantify CA by analyzing the relationship between transient changes in cerebral blood flow and blood pressure. This study attempted to assess whether resting state dCA was a functional predictor of outcome.