American Heart Association

Monthly Archives: July 2018

Article Commentary: “Antibiotic Therapy for Preventing Infections in People With Acute Stroke”

Mark Sabra, MD  

Vermeij J-D, Westendorp WF, Dippel DWJ, van de Beek D, Nederkoorn PJ. Antibiotic Therapy for Preventing Infections in People With Acute Stroke. Stroke. 2018

Infections are common complications in acute stroke patients, whether ischemic or hemorrhagic infarcts. Infections in the hospital setting have been associated with worse outcomes in stroke patients from a morbidity/mortality standpoint. The two most common infections that were studied were urinary tract infections and pneumonia. This publication was updating the completion of a meta-analysis that started in 2012.

Results were obtained by meta-analysis of databases, trial registers, references and randomized controlled trials. Of the 8 trials that were chosen, there were 4488 patients total with 2230 receiving preventive antibiotics vs. 2258 not receiving antibiotics.

AHA Scientific Statement on Intracranial Endovascular Procedures and the Evidence Behind Them

Gurmeen Kaur, MBBS

Eskey CJ, Meyers PM, Nguyen TN, Ansari SA, Jayaraman M, McDougall CG, et al. Indications for the Performance of Intracranial Endovascular Neurointerventional Procedures: A Scientific Statement From the American Heart Association. Circulation. 2018

Endovascular intracranial procedures have seen significant advances over the past 3-4 years as reflected in all the recent stroke thrombectomy trials. Given that the last scientific review by the American Heart Association was in 2009, this Scientific Statement document updates the review of outcomes data for the efficacy and safety of these procedures and provides new recommendations for the use of these therapies.

A highly selected writing group did a computerized search of the National Library of Medicine database of literature (PubMed) from July 2007 to January 2016 to come up with these recommendations.