Statins and Carotid Artery Stenting
Tapan Mehta, MBBS, MPH
Hong JH, Sohn SI, Kwak J, Yoo J, Chang HW, Kwon OK, et al. Dose-Dependent Effect of Statin Pretreatment on Preventing the Periprocedural Complications of Carotid Artery Stenting. Stroke. 2017
In this entry, I discuss a recent publication by Dr. Jeong-Ho Hong and colleagues regarding effectiveness of statin pretreatment on preventing the periprocedural complications of carotid artery stenting (CAS).
CAS as a procedure has evolved significantly in the past two decades. Previous studies have shown increased periprocedural complication risk with CAS compared to carotid endarterectomy (CEA). Invention of new endovascular devices, distal embolization protection systems and antiplatelet medications, along with increasing operator experience, have contributed in reduction of periprocedural complications. Recently published CREST trial data can be considered an important example of this. As there is already data available on statin pretreatment reducing periprocedural complication risk for CEA and percutaneous coronary intervention, this study importantly extends the possibility of benefit with pre-procedural statin use for patients undergoing CAS.