Improved Diagnostic Accuracy of Non-Occlusive Intracranial Vasculopathies With the Use of Vessel Wall Imaging
Sami Al Kasab, MD
Mossa-Basha M, Shibata DK, Hallam DK, de Havenon A, Hippe DS, Becker KJ, et al. Added Value of Vessel Wall Magnetic Resonance Imaging for Differentiation of Nonocclusive Intracranial Vasculopathies. Stroke. 2017
The term intracranial vasculopathy denotes any disease affecting the blood vessels of the brain and meninges. This includes vascular abnormalities due to inflammatory, metabolic, or hereditary conditions; coagulopathy-related disorders; and functional disorders of the blood vessels. Differentiating the type of vasculopathy is important, as treatment is different depending on the type of vasculopathy. Most common intracranial vasculopathies include intracranial atherosclerosis (ICAD), reversible cerebral vasoconstriction syndrome (RCVS), and infectious/inflammatory vasculopathies (IVas).
Recently, intracranial vessel imaging with magnetic resonance imaging (MRI) has emerged as a promising modality to characterize intracranial vasculopathies. Intracranial vessel imaging with MRI has been used to characterize vessel wall as well as vessel lumen. In this study, Mossa-Basha and colleagues compare the diagnostic accuracy of intracranial vessel wall MRI (IVWI) with luminal imaging to luminal imaging alone in non-occlusive vasculopathy differentiation such as ICAD, RCVS, and IVas.