External validation of the SICH-score
Sebina Bulic, MD
van Asch CJJ, Velthuis BK, Greving JP, van Laar PJ, Rinkel GJE, Algra A, et al. External Validation of the Secondary Intracerebral Hemorrhage Score in The Netherlands.Stroke. 2013
Despite considerable research advances, management of ICH remains devastating event with considerable morbidity and mortality. In 2010 Delgado Almandoz at al published a. groundbreaking scoring system; The Secondary Intracerebral Hemorrhage (SICH) score for assessment of patient’s risk of harboring an underlying vascular etiology for ICH. This score has been successfully externally validated and used in the USA.
Univariable logistic regression analysis was performed for each of the separate SICH items, as well as SICH score using original regression coefficient of the multivariable model originally used. Discriminative ability in the validation cohort was modest (which improved with the application of the original regression coefficient). Calibration was found to be modest as well. Non contrast CT scan analysis was found to be strongest predictor for the underlying vascular malformation, thus Non contrast CT analysis was endorsed by the authors rather than SICH score.