Like other recently published data, the STAR trial suggests stentrievers result in higher rates of revascularization and lower rates of complications. The secondary outcome, a mRS of 0-2 at 90 days, of 58% is significantly higher than previously reported data. For comparison, the same result in SYNTHESIS, IMS-III, and SWIFT, which also used Solitaire, was 41%, 42%, and 37%. That’s what happens when you cherry-pick patients with small areas of infarct on imaging, premorbid mRS ≤2, and only anterior circulation occlusion. As a result, this trial does not change management, but it does wet my appetite for upcoming prospective randomized trials comparing second-generation stentrievers to IV t-PA.
The band plays on: excellent revascularization and neurologic outcome with the Solitaire stentriever
Like other recently published data, the STAR trial suggests stentrievers result in higher rates of revascularization and lower rates of complications. The secondary outcome, a mRS of 0-2 at 90 days, of 58% is significantly higher than previously reported data. For comparison, the same result in SYNTHESIS, IMS-III, and SWIFT, which also used Solitaire, was 41%, 42%, and 37%. That’s what happens when you cherry-pick patients with small areas of infarct on imaging, premorbid mRS ≤2, and only anterior circulation occlusion. As a result, this trial does not change management, but it does wet my appetite for upcoming prospective randomized trials comparing second-generation stentrievers to IV t-PA.
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